• High surface coverage and exhaustive double end-capping


• Excellent peak shape for acids, bases and neutrals


• High performance over a wide pH range (pH 1.5 – 10.0)


• Exceptional batch-to-batch and column-to-column reproducibility


• Typical reversed phase retention and selectivity, with less retention than C18


• Recommended for higher hydrophobic compounds and LC/MS applications


• Available in dimensions from analytical to preparative for all sample sizes

WelchromTM XB-C8 phase is prepared using the same bonding chemistry and end-capping technique as is WelchromTM XB-C18 phase. This phase provides excellent peak shapes for polar and basic compounds, long lifetime and stability in a wide pH range. The following chromatograms show excellent peak shapes for TCAs.
The XB-C8 phase is less retentive than XB-C18 phase, more useful for compounds that are too strongly retained on C18 phase, and for LC/MS applications, where long retention is not required. The following shows retention comparison of XB-C18 and XB-C8 on neutral compounds and on weak and polar compounds. When separating neutral or other highly retained compounds, XB-C8 can save analytical time. However, when separating polar compounds, XB-C8 columns provide alternative selectivity from XB-C18 columns.

Recommended Substitute For: